Treatment of alcoholic hepatitis: is this a "dead-end"?

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Treatment of alcoholic hepatitis: is this a “dead-end”?

Alcoholic hepatitis (AH) is a clinical syndrome characterized by jaundice and liver failure that develops in subjects with chronic and active alcohol abuse [1]. The shortterm mortality in patients with severe disease, as defined by the Maddrey’s discriminant function, exceeds 30% [2]. Up to now, only two drugs, prednisolone and pentoxifylline, have shown some efficacy for the treatment of this ...

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Alcoholic hepatitis: Prognosis and treatment.

Alcoholic hepatitis (AH) is a type of acute-on-chronic liver failure and is the most severe form of alcoholic liver disease. AH occurs in patients with heavy alcohol abuse and underlying liver disease. In its severe form, AH carries a poor short-term prognosis. Although the existence of AH can be strongly suspected based on clinical and biochemical criteria, a definitive diagnosis requires a li...

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Alcoholic hepatitis is a precirrhotic lesion; it develops in only a minority of chronic alcohol abusers even after decades of abuse The clinical spectrum of disease varies from asymptomatic hepatomegaly to florid hepatocellular failure with gastrointestinal bleeding and hepatic encephalopathy. Corresponding variation is observed both in morbidity and mortality. The majority of individuals with ...

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ژورنال

عنوان ژورنال: Annals of Gastroenterology

سال: 2016

ISSN: 1792-7463

DOI: 10.20524/aog.2016.0023